Natto is a traditional Japanese food consisting of soybeans
fermented with Bacillus subtilis. Its history traces back over
1,000 years, with over 200,000 tons being consumed in Japan
during 2008 alone. As a food, natto is viscous and odiferous in a
way that may be expected of a fermented product. -wise,
there are two important constituents often associated with natto
- K2 (in the form of MK-7), and nattokinase, a
fibrin-dissolving enzyme. One of K’s most prominent roles
is assisting with blood-clotting by helping to produce
clotting-factors. Nattokinase, however, is involved in the
site process. This is sometimes the conundrum with natto. In
fact, many practitioners rightly advise patients taking
blood-thinning medication to avoid natto due to the K
content. This is despite the support nattokinase may offer in
helping balance clot formation and degradation.* Others with soy
ies, or those who simply have a distaste for natto, cannot
access the benefits of natto. Fortunately, Jarrow Formulas
NattoMax provides purified nattokinase that is both free-from
K and safe for people with soy ies.
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Distinguishing Features:
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* Prolonged efficacy compared to alternatives
* Purified enzyme without adulterants
* K free
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Blood Clotting Balance*
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The bio cascade that leads to blood-clotting, the first
step in a wound healing, is both complex and life-preserving.
Without it, a minor cut could lead to an untimely demise. At the
center of this process is fibrin, a fibrous protein produced by
an enzyme, thrombin, which is activated when the body senses
clotting is required. Upon healing the fibrin is covered over by
normal tissue, while another set of proteins (e. g. plasmin)
helps to dissolve the now unnecessary fibrin. This is the normal
process at the site of a wound, but as we age, or under certain
physiological conditions, the ability to dissolve fibrin tends to
fall out of balance with the ability to create fibrin.
When fibrin accumulates in blood vessels, blood begins to flow
less freely. This can reduce oxygen transport to heart and brain
tissue, resulting in suboptimal function. Meanwhile, the excess
fibrin can make blood vessels less pliable and lead to elevated
blood pressure. Nattokinase helps to maintain proper blood
viscosity, fibrin levels, and y circulation, all effects
that draw support from research conducted at the National
Cardiovascular Center in Japan.*
Nattokinase, Circulation, And Enzyme Digestion
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Nattokinase is believed to do a number of things in promoting
circulatory .* First, it acts as a natural fibrinolytic
(clot-dissolving) enzyme that helps to support the body’s ability
to regulate fibrin.* In fact, this is why nattokinase is measured
in terms of fibrinolytic units (FU). And some research suggests
that nattokinase is more effective than the body’s own enzyme,
plasmin, for this purpose. Second, nattokinase appears to support
normal levels of plasminogen activator inhibitor 1 (PAI-1). High
levels of PAI-1 can negatively impact fibrin degradation by
reducing the plasminogen levels that are critical to the
production of plasmin. By maintaining normal levels of PAI-1,
nattokinase supports the body’s own fibrin-dissolving
mechanisms.*
Ingesting an enzyme raises an interesting question: if an enzyme
is merely a protein, won’t it be digested and inactivated in the
intestines? There’s little doubt that some of the nattokinase is
broken down into smaller protein fragments and amino s, but
it seems that a significant portion is absorbed, fully
functional. Yet even more interesting is research suggesting that
fragments of nattokinase, generated upon digestion, have
circulatory- activity too. This does not come as a huge
surprise since other food-source protein fragments, such as those
from sesame and milk , possess biological activity. But what may
be less expected is that fragments of nattokinase appear to
possess distinct and complementary effects to that of the whole
enzyme. For instance, researchers found that nattokinase
fragments interacted with angiotensin II, a peptide hormone that
helps regulate blood pressure via action on other enzymes such as
renin and acetycholineesterase. Whole nattokinase does not do
this. This means that the action of digestion on nattokinase may
actually be beneficial, not detrimental.
*These statements have not been evaluated by the Food and Drug
Administration. This product is not intended to diagnose, treat,
cure, or prevent any disease.
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- About this item Supports y Circulation Purified Nattokinase Veggie s 2000 FU (100 mg) Per During the summer months products may arrive warm but desertcart stores and ships products in accordance with manufacturers' recommendations, when provided..